Many communities in the United States are confronted by unacceptable levels of crime and violence on our streets. Typically, a disproportionate amount of this violence is the result of young males killing other young males. In the United States, homicide is the second leading cause of death for all young males 15–24 years old. According to the National Center for Injury Prevention and Control, homicide is the leading cause of death among 10–24-year-old African Americans. This is simply unacceptable. It is imperative that law enforcement works with our partners in the criminal justice system to reduce the level of violence through an array of successful approaches. These range from early intervention, to aggressive enforcement and prosecution, to enhanced penalties for those that commit crimes with a firearm. This guide was developed as part of an IACP Presidential Initiative and designed for the purpose of providing an action agenda for law enforcement leadership, their agencies, and the communities they serve.